Guowen Changchun International Hospital

Diagnostic Pathology Centre

Niu ChunBo

Director of pathology, Chief physician
Postdoctoral Fellow in Medicine
Graduate student supervisor
Chunbo Niu,resigned from the position of professor of Pathology in China-Japan Union Hospital of Jilin University and joined the Guowen Medical corporation Changchun hospital.
Her research interests include chest neoplasms, thyroid and mammary glands, respiratory system, lymphopoietic system tumors, and molecular pathology. She is good at the detection and diagnosis of tumor properties, tumor classification, and molecular pathology, and has rich clinical experience and profound theoretical basis.

Department introduction

Rapid pathological diagnosis was carried out to optimize surgical treatment.The pathological diagnosis results are recognized nationally.The department synchronized the pathological diagnosis system of Peking University Cancer Hospital and Fudan University Cancer Hospital in Shanghai, strictly implemented the pathological operation specifications of each system, established the whole process of high-quality work flow of preoperative biopsy, intraoperative freezing and postoperative pathology, and established a perfect quality control and quality assurance system of pathological diagnosis. In addition, the latest research results and clinical and pathological guidelines at home and abroad are constantly followed, especially the CSCO cancer diagnosis guidelines, NCCN clinical practice guidelines, pathological guidelines of various systems, pathological diagnosis and molecular diagnosis basis and indicators are kept updated in a timely manner.The department of pathology is equipped with the worlds advanced equipment such as Roche automatic immunomogizing machine, Leica automatic immunomogizing machine, multi-person microscope, automatic section scanning, etc., which can carry out dozens of molecular pathological testing projects applied in pathological diagnosis and targeted therapy.

Carry out the project

1、Histopathological examination and diagnosis

①Local excisional tissue biopsy

②Surgical specimen examination

③Puncture tissue biopsy

④Endoscopic tissue biopsy

⑤Intraoperative frozen section examination

⑥Bone marrow biopsy

2、Cytopathological examination and diagnosis

①Cytological examination of body fluid

②Fine needle aspiration cytology examination

③Exfoliative cytology examination

3、Special staining diagnostic techniques

①Special staining and enzyme histochemical staining

②Immunohistochemical staining

4、Molecular genetic diagnosis laboratory test items

①Breast cancer, gastric cancer, etc.: Her-2 gene amplification detection, BRCA gene mutation detection, MSI detection, pan solid tumor 425 gene detection, HER-2 gene amplification detection, POLE gene (4 hot spots) detection

②Glioma: IDH1, IDH2, TERT gene mutation detection; MGMT gene methylation detection; 1p/19q co-deletion detection

③Lung cancer, colorectal cancer, gastric cancer, etc.: EGFR (including blood T790m)/KRAS/BRAF gene mutation detection, EML4-ALK, ROS-1 fusion gene detection, CTC (folate receptor positive circulating tumor cells) detection, lung cancer 9+1 gene mutation detection, lung cancer 6 gene (14 gene) mutation detection, lung cancer 139 gene detection, pan solid tumor 425 gene detection, intestinal cancer/lung cancer 10 gene mutation detection, MSI detection

④Lymphoma: IgK, IgH, IgL, TCRB, TCRG, TCRD gene rearrangement detection

⑤Gastrointestinal mesenchymal tumor: c-kit, PDGFRα gene mutation detection

(6) HPV genotyping test

(vii) Mycobacterium tuberculosis detection, etc.

⑧EBER in situ hybridization test

⑨Thymidine kinase 1 (TK1) cell cycle detection

5、Difficult pathology consultation

6、Pathological autopsy

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